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This article is about a dietary therapy for epilepsy. A test strip is compared with a colour chart that indicates the degree of ketonuria. The ketone bodies pass into the brain and replace glucose as an energy source. Almost half of children, and young people, with epilepsy who have tried some form of this diet saw the number of seizures drop by at least half, and the effect persists even after discontinuing the diet. This classic ketogenic diet contains a 4:1 ratio by weight of fat to combined protein and carbohydrate. This is achieved by excluding high-carbohydrate foods such as starchy fruits and vegetables, bread, pasta, grains and sugar, while increasing the consumption of foods high in fat such as nuts, cream and butter. MCTs, to provide around half the calories.
As less overall fat is needed in this variant of the diet, a greater proportion of carbohydrate and protein can be consumed, allowing a greater variety of food choices. Charlie Foundation to promote it. The foundation sponsored a multicentre research study, the results of which—announced in 1996—marked the beginning of renewed scientific interest in the diet. As of 2012, there is limited clinical trial data in these areas, and, outside of paediatric epilepsy, use of the ketogenic diet remains at the research stage. This might affect, for example, the muscles, the senses, consciousness, or a combination. Although popular in the 1920s and 30s, it was largely abandoned in favour of new anticonvulsant drugs.